PYSEC-2026-2772
Open Babel has NULL pointer dereference in CACAO CacaoFormat::SetHilderbrandt
Quick fix
PYSEC-2026-2772 — openbabel: upgrade to the fixed version with the command below.
pip install --upgrade 'openbabel>=3.2.0'Details
### Summary
A memory-safety vulnerability in Open Babel's CACAO parser caused a NULL pointer dereference when reading a crafted input file.
### Details
The flaw was in `CacaoFormat::SetHilderbrandt`. A malformed input caused the parser to dereference a NULL pointer while applying the Hilderbrandt transformation.
### Impact
Open Babel is a C++ library and CLI used to read and write chemistry file formats; it is shipped by Linux distributions and embedded in services that may parse untrusted input. Triggering this vulnerability requires the victim to open a malicious CACAO file with the `obabel` tool, the `OBConversion` API, or any of the language bindings (Python, Ruby, Java, R, Perl, C#, PHP).
### Affected versions
All releases up to and including 3.1.1.
### Patched version
3.2.0 (released 2026-05-26).
### Patch
Fix commit: https://github.com/openbabel/openbabel/commit/ecaed96f Originally reported as #2827; fixes consolidated in #2913.
A minimized reproducer for this CVE is checked in under `test/files/fuzz_regress/` and is exercised on every CI build under ASAN+UBSAN by the `fuzzregresstest` harness.
### Credit
Reported via OSS-Fuzz.
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Affected packages
References
- https://github.com/openbabel/openbabel/security/advisories/GHSA-55j6-rjhx-hwfh[WEB]
- https://nvd.nist.gov/vuln/detail/CVE-2025-10999[ADVISORY]
- https://github.com/openbabel/openbabel/issues/2827[WEB]
- https://github.com/openbabel/openbabel/commit/ecaed96f[WEB]
- https://github.com/openbabel/openbabel[PACKAGE]
- https://github.com/user-attachments/files/22318503/poc.zip[WEB]
- https://vuldb.com/?ctiid.325927[WEB]
- https://vuldb.com/?id.325927[WEB]
- https://vuldb.com/?submit.654064[WEB]
- https://pypi.org/project/openbabel[PACKAGE]
- https://github.com/advisories/GHSA-55j6-rjhx-hwfh[ADVISORY]